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The effect of perioperative intravenous infusion of lidocaine on pulmonary protection and postoperative quality of recovery in neurosurgical patients

The effect of perioperative intravenous infusion of lidocaine on pulmonary protection and postoperative quality of recovery in neurosurgical patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069253
Enrollment
Unknown
Registered
2023-03-10
Start date
2023-03-10
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pulmonary complications

Interventions

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years; 2. Patients receiving neurosurgery under elective general anesthesia; 3. ASA grade I-III; 4. Those who agree to participate in the experiment and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. History of mechanical ventilation 2 weeks before surgery; 2. History of sepsis or acute respiratory failure 2 weeks before surgery; 3. BMI>==30kg/m^2 or weight <40kg; 4. Those who need emergency surgery; 5. Known intolerance or allergy to lidocaine; 6. Patients with severe liver and kidney dysfunction; 7. Adams-stokes syndrome, pre-excitation syndrome, severe heart block (including sinus, atrioventricular and intraventricular block); 8. Get involved in other research.

Design outcomes

Primary

MeasureTime frame
Postoperative pulmonary complications;

Secondary

MeasureTime frame
Quality of Recovery Scale (QOR-40) score;Serological indicators ;a/A value;Total opioid consumption after operation;Postoperative pain level;Length of stay;Occurrence of adverse events;

Countries

China

Contacts

Public ContactChen Xiuxia

The Affiliated Hospital of Xuzhou Medical University

cxxlxy@sina.com+86 15205200798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026