Vascular cognitive impairment (VCI)
Conditions
Interventions
intervention group:music listening
Sponsors
Fu Xing Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=50 years; 2. Meet the VCI diagnostic criteria in the 2019 Chinese Guidelines for Diagnosis and Treatment of Vascular Cognitive Impairment; 3. MoCA=8 score; 5. Imaging suggests cerebrovascular disease (cerebral infarction, cerebral hemorrhage, leukoencephalopathy, microhemorrhage, perivascular space); 6. More than 3 months after the onset of stroke.
Exclusion criteria
Exclusion criteria: 1. There are other neurological diseases that may affect cognitive function, such as AD, Parkinson's disease, frontotemporal degeneration, brain trauma, central nervous system infection, etc.; 2. Have serious physical dysfunction, can not cooperate to complete the scale assessment; 3. Serious mental illness; 4. Antibiotics, probiotics or prebiotics should be used within 1 month; 5. The dose of improved smart drugs or anti-anxiety and depression drugs has been adjusted in the past 6 weeks; 6. There are contraindications to MRI examination; 7. The patient is in critical condition with unstable vital signs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment Scale Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuropsychiatric Inventory (NPI);Digit Symbol Substitution Test;Stroop Color Word Test;Clock Drawing Test;Hamilton Anxiety Scale;Hamilton Depression Scale;Pittsburgh Sleep Index;Mini Nutritional Assessment Scale;Boston Naming Test; | — |
Countries
China
Contacts
Public ContactLiu Jianjian
Fu Xing Hospital, Capital Medical University
Outcome results
None listed