Non-small cell lung cancer
Conditions
Interventions
Group OFA:thoracic paravertebral block, esketamine, dexmedetomidine
Group OBA:opioid-based anesthesia and analgesia
Sponsors
Beijing Friendship Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients scheduled to undergo VATS partial pneumonectomy, aged >18 years and ASA grade ? - ?.
Exclusion criteria
Exclusion criteria: 1. Allergic or contraindicated to study drugs; 2. Chronic pain; 3. Severe liver dysfunction (total bilirubin >=2mg/dl); 4. Severe renal dysfunction (glomerular filtration rate 30kg m^2; 8. Dementia or obvious neurological diseases (such as stroke, epilepsy, intracranial tumors, Parkinson's disease history, etc.); 9. History of alcohol or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 15-item recovery quality scale (QoR-15) 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 score 48 hours after surgery;3-minute diagnostic interview for CAM;Overall benefit of analgesic score satisfaction in pain treatment;Acute pain numeric rating scale score;Dosage of postoperative analgesics;Intensity of patient's chronic pain at rest; | — |
Countries
China
Contacts
Public ContactWan Lei
Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed