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Study on rehabilitation effect of multiple neuromodulation techniques in patients with brain injury

Study on rehabilitation effect of multiple neuromodulation techniques in patients with brain injury

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069203
Enrollment
Unknown
Registered
2023-03-09
Start date
2023-03-11
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain injury

Interventions

control group:Traditional standardized rehabilitation intervention
intervention group of brain injury hemiplegia:Intervention of neuroregulation technology
brain injury hemiplegia combined with aphasia group:Intervention of neuroregulation technology

Sponsors

China Rehabilitation Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Hemiplegia patients with brain injury: (1) Patients aged 3-60 years, with a disease course of >=1 year in patients with brain trauma or stroke; (2) The course of disease of patients with hemiplegic cerebral palsy >=3 years; (3) All the above patients with brain injury had hemiplegia and spasm before surgery, and the modified Ashworth scale >= level 2; (4) No extrapyramidal symptoms such as ataxia; (5) MMSE score >=22 points; (6) Sign informed consent. 2. Patients with brain injury hemiplegia combined with aphasia: (1) Except for spastic hemiplegia, the patients conforming to the above brain injury were confirmed as non-fluent aphasia by the Western Aphasia Checklist, right-handed, and the lesions were confined to the left cerebral hemisphere; (2) Except severe cognitive impairment, can cooperate with examination and treatment; (3) Normal speech function before onset, and native Chinese; (4) Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with mental disorders or cognitive dysfunction in the past or at the present stage; 2. Patients with malignant tumors, severe infections, and serious cardiopulmonary diseases; 3. Patients with fracture, limb deformity or joint contracture; 4. Severe depression (HAMD>=24 points); 5. The patient cannot undergo magnetic stimulation therapy or MRI examination due to metal foreign bodies or other implanted devices in the body; 6. Unwilling to cooperate, unable to conduct tests and assessments.

Design outcomes

Primary

MeasureTime frame
Related scale of limb function level;Western Aphasia Checklist;Barthel Index;Hamilton Depression Scale and Anxiety Scale;Functional magnetic resonance;

Countries

China

Contacts

Public ContactLiu Lixu

China Rehabilitation Research Center

liulixu2004@163.com+86 136 7126 2202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 20, 2026