respiratory distress
Conditions
Interventions
Transnasal continuous positive airway pressure group (nCPAP) group:nCPAP
Transnasal intermittent positive pressure group (nIPPV) group:nIPPV
Sponsors
West China Second University Hospital,SCU
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Infants will be included in the trial if : 1.1. They are born at =32 weeks GA ; and 1.2. They are 0.3 for more than 1 hour to maintain peripheral oxygen saturation (SpO2) 90% to 94% 1.4. parental consent is obtained.
Exclusion criteria
Exclusion criteria: Infants will be excluded from the trial if: 2.1.They have previously been intubated, or need intubation within 24 hours after admission as determined by the attending pediatrician; or 2.2.They have a known major congenital anomaly which may have impact on the infant s condition after birth (e.g. complex congenital cardiac disease, congenital diaphragmatic hernia; upper airway malformations, Pierre Robin, cleft lip and palate, gastrointestinal malformation, or chromosomal abnormalities); or 2.3.They have neuromuscular disorders; or 2.4.They have contraindications of using non-invasive ventilation (e.g.pneumothorax without puncture drainage); or 2.5.They die or leave the NICU within 24 hours after admission; or 2.6.Their parents don't provide agreement or refuse to allow their participation before randomization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment failure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total duration of respiratory support;Duration of oxygen therapy;Duration of admission;Age of total enteral nutrition;Necrotizing enterocolitis;Bronchopulmonary dysplasia;Cost-effectiveness of admission;Mortality;EDIN scale; | — |
Countries
China
Contacts
Public ContactXiong Tao
West China Second University Hospital,SCU
Outcome results
None listed