negative postoperative behavioral changes
Conditions
Interventions
Group A(DPNB):Dorsal Penile Nerve Block
Group B(Esketamine0.5mg/kg):Esketamine0.5mg/kg intravenous injection
Group C(Esketamine0.5mg/kg+DPNB):Esketamine0.5mg/kg intravenous injection?Dorsal Penile Nerve Block
Sponsors
Shunde Hospital of Southern Medical University
Eligibility
Sex/Gender
Male
Age
4 Years to 8 Years
Inclusion criteria
Inclusion criteria: From March 2023 to August 2023, children who underwent circumcision under intravenous general anesthesia (operation time: 5min-30min) were selected in our hospital; Age (4-8y); Body mass index: 14.8 19.6kg/m2; ASA I level; Intelligence and language development are within the normal range, and normal language communication can be conducted.
Exclusion criteria
Exclusion criteria: 1) Those who refused to participate in the study; 2) Known neurological or cognitive impairment; 3) Parents or guardians are unable to understand the study or express consent due to illiteracy or language difficulties; 4) Preoperative history of congenital, hereditary and psychiatric diseases; 5) Recent history of upper respiratory tract infection or obstructive symptoms; 6) Premature birth or chronic history; 7) Developmental delay; 8) Children with significant life changes in their families recently (such as family death, moving to a new home, changing to a new kindergarten, etc.); 9) Allergic history of local anesthetics, aspirin, ketorolac, tromethamine and other non steroidal drugs; 10) Abnormal bleeding and coagulation; 11) History of digestive tract ulcer; 12) History of neuromuscular diseases: 13) Contraindications of dorsal penile nerve block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PHBQ score; | — |
Secondary
| Measure | Time frame |
|---|---|
| FLACC score;PAED score;Intraoperative propofol additional quantity;Intraoperative respiratory depression and body dynamic response;The wake up time;The PACU stay time;Adverse reactions such as nausea, vomiting, itching of the number of cases;Postoperative oral ibuprofen suspension remedy cases of analgesia; | — |
Countries
China
Contacts
Public ContactLi Shujia
Shunde Hospital of Southern Medical University
Outcome results
None listed