Intraoperative hypoxemia
Conditions
Interventions
Esketamine group:Esketamine
Control group:Intravenous sufentanil (5-10 µ g) Propofol (1-1.5 mg/kg) induced anesthesia.
Sponsors
Huadong Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients who plan to undergo intravenous anesthesia for minor surgery; (2) Those who are 65 years old or above, male or female, and have the ability to act independently; (3) The American Association of Anesthesiologists (ASA) is rated as I – III.
Exclusion criteria
Exclusion criteria: (1) Have a history of myocardial infarction and unstable angina pectoris in the past 6 months; (2) Have a history of severe arrhythmia, acute pharyngitis and tonsillitis; (3) Pneumonia or non-oxygen pulse blood oxygen saturation (SPO2)<90%; (4) Severe obstructive sleep apnea syndrome; (5) Allergies to propofol, eggs, soy or albumin; (6) Do not agree to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of severe hypoxemia;Duration of hypoxemia;lowest oxygen saturation;Proportion of emergency airway management;Operation time;recovery time;Satisfaction of anesthesiologists and surgeons;adverse event; | — |
Countries
China
Contacts
Public ContactYIN, Xin
Huadong Hospital Affiliated to Fudan University
Outcome results
None listed