Skin aging
Conditions
Interventions
Group 1:Oral collagen tripeptide powder
Group 2:Oral collagen tripeptide and elastin peptide mixed preparation
Sponsors
Institute of Nutrition and Health, Qingdao University
Eligibility
Sex/Gender
Female
Age
30 Years to 55 Years
Inclusion criteria
Inclusion criteria: Healthy women aged 30-55 years; Dry skin on the forearms according to self-assessment; Photo types I-IV (Fitzpatrick scale); Good general health and mental condition; Consent to the trial process and sign the informed consent form; Attend in person at the study group appointment time and be willing and able to adhere to the study rules and flow charts.
Exclusion criteria
Exclusion criteria: Acute skin conditions (such as allergic eczema, neurodermatitis or psoriasis) or other skin conditions (such as scarring, sunburn or moles) in the test skin area; Food allergy to the ingredients of the test product; gastrointestinal disorders or dyspepsia; Test for tattoos on the skin area; Topical administration in the test skin area within 6 weeks prior to study start; systemic use of anti-inflammatory drugs or antibiotics in the 2 weeks prior to study start; systemic administration of corticosteroids and/or antihistamines within 4 weeks prior to study start; other systemic medications within 4 weeks prior to study start; Participants present with systemic illness at the start of the study; Pregnancy or lactation; Immune disorders; severe medical conditions (e.g. cancer, acute cardiac and circulatory disorders, severe diabetes, alcohol or drug abuse) within the six months prior to study start; Participate in other cosmetic trials conducted on the test skin area within 2 weeks prior to or during the study; Participation in the study of pharmaceutical preparations within 4 weeks prior to the start of the study; intake of nutritional supplements (except for the test product) within 4 weeks prior to study start and during the study; changes in lifestyle or eating habits during the study period; treatment with make-up remover products or oily or moisturizing skin cleansers on the arm; changing daily skin care routines; Strong sun exposure or artificial UV exposure (sunbathing) to the test area before the start of the study or for 1 week during the study; swimming, sauna or high-intensity exercise within 1 day prior to measurement; Lack of adherence, intellectual or mental inability to follow study instructions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin elasticity;Skin wrinkles;Skin pores;Skin tone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin microbiota;Skin metabolites;Fecal microbiota;Fecal metabolites;Blood biochemistry;Urine metabolites; | — |
Countries
China
Contacts
Public ContactJin Sun
Institute of Nutrition and Health, Qingdao University
Outcome results
None listed