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Comparison of two basal glargine in hospitalized patients

Comparing the efficacy and safety of U300 glargine and U100 glargine in hospitalized patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069146
Enrollment
Unknown
Registered
2023-03-08
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes

Interventions

U300 glargine:Use U300 glargine to regulate blood glucose. When FBG and 2hBG meet the standard, cross use another basic insulin with the same dose
U100 glargine:Use U100 glargine to regulate blood glucose. When FBG and 2hBG meet the standard, cross use another basic insulin with the same dose

Sponsors

The Second Affiliated Hospital, Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: The patient was diagnosed with T2DM, and the newly diagnosed patient's glycosylated hemoglobin (HbA1C) = 9.0% or fasting blood glucose (FPG) = 11.1 mmol/L, or the patient with HbA1C = 7.0% after three months of pharmacologoc therapy, 18-75 years old, with no abnormal liver function and glomerular filtration rate (eGFR)>45, agreed to use insulin treatment.

Exclusion criteria

Exclusion criteria: (1)Pregnant or lactating women (2)Who are or may be allergic to insulin glargine, insulin detemir, Insulin Aspart or its components (3)Diabetic ketoacidosis, severe infection, severe trauma (4) Severe hepatic and renal dysfunction (5) T1DM and other special type of diabetes mellitus (DM) (6) Any other disease considered by the investigator to be likely to interfere with participation in the pilot study or evaluation

Design outcomes

Primary

MeasureTime frame
Midnight blood glucose;fasting blood glucose;blood glucose before three meals;blood glucose 2 hours after three meals;blood glucose before sleep;insulin dosage;duration achieving target;

Secondary

MeasureTime frame
hypoglycemia;

Countries

China

Contacts

Public ContactWangen Li

The Second Affiliated Hospital, Guangzhou Medical University

liwg660@126.com+86 13500031715; 020-34152268

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026