Very low birth weight infant
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Very low birth weight infants (=1500g) who are intubated within 1h after birth and have been on the ventilator for more than 24h (2) Very low birth weight infants who were intubated outside our facility and have been transferred to our hospital within 1 hour.
Exclusion criteria
Exclusion criteria: (1) Fatal congenital malformations (2) Diaphragmatic hernia, meconium aspiration syndrome, air leak syndrome, massive pleural effusion (3) Used high frequency ventilation after admission (4) Refusal to participate in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Death;Bronchopulmonary dysplasia, BPD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time on invasive mechanical ventilation;time on noninvasive mechanical ventilation;Length of hospitalization;length of oxygen use;Failure of conventional mechanical ventilation;Rescue therapy of HFOV;reintubation;Pulmonary hemorrhage;Air leak syndrome;IVH(>3-4);PVL;Retinopathy of premature infants, ROP;Patent ductus arteriosus, PDA;Necrotizing enterocolitis, NEC; | — |
Countries
CHINA
Contacts
West-China second hospital, Sichuan University