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Ocular imaging biomarkers for attention deficit hyperactivity disorder (ADHD)

Ocular imaging biomarkers for attention deficit hyperactivity disorder (ADHD)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069141
Enrollment
Unknown
Registered
2023-03-08
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention deficit hyperactivity disorder (ADHD)

Interventions

ADHD children:Ophthalmic examination including OCT-A imaging
Normal children:Ophthalmic examination including OCT-A imaging

Sponsors

Research Office, Health Bureau
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 8 Years

Inclusion criteria

Inclusion criteria: - Children with ADHD history or previously diagnosed as ADHD in hospitals will be included. - Agree and/or have parent(s) and/or guardian(s) who agree to join the study by signing written assent and/or informed consent or had parent(s) and/or guardian(s) who signed a former written informed consent which stated their acknowledgement of the use of the collected tissues for future studies

Exclusion criteria

Exclusion criteria: Children with any ocular diseases except refractive error

Design outcomes

Primary

MeasureTime frame
Changes of RNFL, GCL, retinal vasculature (CRAE and CRVE), retinal microvasculature (FAZ area, FAZ circularity, VD, VDI and FD), choroidal thickness, and choroidal vasculature (CVI) between ADHD, severity of ADHD and normal children;Difference of RNFL, GCL, retinal vasculature (CRAE and CRVE), retinal microvasculature (FAZ area, FAZ circularity, VD, VDI and FD), choroidal thickness, and choroidal vasculature (CVI) for ADHD prognosis (between recovered ADHD children/ADHD with good treatment effect);

Secondary

MeasureTime frame
The above difference between ADHD and normal children at baseline;The above difference between children of different severity of ADHD and normal children at baseline;Possible cut-off of these ocular imaging parameters to identify the high risk of ADHD below or within a special point of these imaging parameters;

Countries

Hong Kong

Contacts

Public ContactDr ZHANG Xiujuan

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong

zhangxiujuan@cuhk.edu.hk+852 39435895

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026