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Study on the pregnancy outcome of adding rLH at different times in the elderly women undergoing IVF

Study on the pregnancy outcome of adding rLH at different times in the elderly women undergoing IVF

Status
Recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069139
Enrollment
Unknown
Registered
2023-03-07
Start date
2022-09-29
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women infertility

Interventions

Group A: If LH=0.5mIU/ml on the Gn initial day, rFSH 225-300IU/d together with rLH 75IU/d was added from the initial day to hCG day:None
Group B: If LH>0.5mIU/ml on the Gn initial day, rFSH 225-300IU/d was added from the initial day, while LH 75IU/d was added on Day5 to hCG day:None

Sponsors

Xiamen Women and Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1. Baseline age 35-39 2. Body mass index (BMI) = 18, = 26 kg/m2 3. Baseline serum FSH level (early follicular phase) = 12 IU/L 4. The menstrual cycle is 25-48 days 5. The number of IVF cycles is the first or second 6. Plan to use the GnRH agonist protocol and add recombinant LH

Exclusion criteria

Exclusion criteria: 1. Serious uterine cavity abnormality 2. Endometriosis stage iii - iv or severe adenomyosis 3. Chromosome abnormality 4. History of spontaneous abortion = 3 times Patients with follicular dysplasia or termination of superovulation due to personal factors

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate of first embryo transfer;

Secondary

MeasureTime frame
Serum progesterone on HCG day;E2 on HCG day;Oocyte retrieved;MII egg rate;2PN rate;available embryo rate;High-quality embryo rate;Implantation rate;live birth rate;Cumulative live birth rate;Moderate to severe OHSS rate;

Countries

China

Contacts

Public ContactYingying Shi

Xiamen Women and Children's Hospital

373745151@qq.com+86 18959237879

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026