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GABA neural mechanism in primary motor cortex and impulsivity of NSSI patients:a case-control study

GABA neural mechanism in primary motor cortex and impulsivity of NSSI patients:a case-control study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069131
Enrollment
Unknown
Registered
2023-03-07
Start date
2023-03-07
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-suicidal self-injury

Interventions

non-suicidal self-injury group?:Paired transcranial magnetic stimulation, stop signal task
Health group:Paired transcranial magnetic stimulation, stop signal task

Sponsors

ningbo kangning hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
13 Years to 25 Years

Inclusion criteria

Inclusion criteria: (1) According to the current statistical standard of the definition of youth age by The Public security Department of China (13~25 years old as adolescents), the age of the study was set as 16 ~25 years old, male and female; (2) The diagnostic criteria of NSSI were in line with the diagnostic and Statistical Manual of Mental Disorders (DSM-5). (3) One attending physician evaluated the patient's NSSI behavior scale to determine whether the patient should be enrolled in the group (the number of NSSI behavior occurred 5 times within one year, and the number of NSSI behavior occurred within two weeks before enrollment was not zero); (4) No family history of mental illness; (5) Informed consent of both the patient and the guardian

Exclusion criteria

Exclusion criteria: (1) The patient's mental diagnosis does not meet the NSSI diagnostic criteria; (2) the patients diagnosed with impulse control disorder, ADHD, excretory disorder, autism, eating disorder and other mental diseases are accompanied by NSSI behavior; (3) the patients with schizophrenia and depression, bipolar disorder accompanied by psychotic symptoms; (4) the history of substance abuse; (5) the patient has other serious neurological diseases or physical diseases; (6) previous seizures; (7) Devices installed in the body that are not suitable for paired TMS detection, such as pacemakers, artificial valves and other metal implants

Design outcomes

Primary

MeasureTime frame
short-interval intracortical inhibition (SICI) ;and long-interval intra-cortical inhibition (LICI);Stop signal reactiontime;Symptom checklist,90;Barratt Impulsiveness Scale;

Secondary

MeasureTime frame
OttawaSelf-injuryInventory;The degree of education;smoking;smoking;smoking;drinking;height;gender;

Countries

China

Contacts

Public ContactMa hong

ningbo kangning hospital

mahongnbu@163.com+86 15728046957

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026