Cerebral infarction
Conditions
Interventions
Intervention group:Standardized treatment for early multimodal vascularization in acute ischemic stroke
Control group:Tierrofiban
Sponsors
Kunshan First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) meeting the diagnostic criteria for acute ischemic stroke. (2)Patients with acute stroke who exceed the time window for arterial and venous thrombolysis (contraindications refer to the Chinese Stroke Association Scientific Statement on Intravenous Thrombolysis in Acute Ischemic Stroke and the Chinese Guidelines for Early Endovascular Intervention in Acute Ischemic Stroke 2018). (3)Signed informed consent.
Exclusion criteria
Exclusion criteria: (1)Onset with seizures. (2)Current or significant bleeding disorders within the previous 6 months. (3)history of severe central nervous system damage (e.g., tumor, aneurysm, arteriovenous malformation, intracranial or spinal cord surgery). (4)Patients with psychiatric disorders, including schizophrenia or other psychiatric disorders. (5)Patients with severe hepatic or renal insufficiency. (6)Patients with allergy to tirofiban hydrochloride, thrombocytopenia with previous use of tirofiban hydrochloride, allergy to argatroban, or unsuitable for anti-platelet aggregation. (7)Not signed informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of treatment outcome in the acute phase of cerebral infarction;Assessment of cerebral infarct severity and cognitive function after cerebrovascular hemodialysis;Follow up to evaluate patients for stroke recurrence; | — |
Countries
China
Contacts
Public ContactZhang Yan
Kunshan First People's Hospital
Outcome results
None listed