Comparative study of Remazolam besylate, cyclopofol and propofol combined with low-dose sufentanil in hysteroscopic surgery
Conditions
Interventions
group R:Anesthesia induction: Remazolam besylate 0.2mg/kg+ sufentanil 0.1ug/kg Maintenance of anesthesia: Remazolam besylate 1mg/kg/h
group H:Anesthesia induction: cipofol 0.4mg+ sufentanil 0.1ug/kg Anesthesia maintenance: cipofol 8mg/kg/h
group P:Anesthesia induction: propofol 2mg/kg+ sufentanil 0.1ug/kg Anesthesia maintenance: propofol 8mg/kg/h
Sponsors
Lishui People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? They all meet the standard of hysteroscopic surgery; ? Female aged 18-65 ? No allergy to the anesthetic ingredients used in the study; ?ASA grading is I~II; ?BMI 18-28 kg/? ? Normal mind, able to cooperate with surgery; ? Volunteer to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: ? Combined with malignant tumor; ? Weak body, unable to tolerate surgery; ? Complicated with serious heart, liver and kidney system diseases; ? Pregnancy and lactation; ? Known or suspected to be allergic or contraindicated to various components of the study drug or other benzodiazepines, opioids, propofol, etc; ? Those who have participated in any clinical trial as subjects within 3 months before enrollment; ? Incomplete clinical data ? Other conditions determined by the researcher to be unsuitable for selection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure;oxygen saturation;heart rate;Rate of respiration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Observer's assessment alert/Sedation;wake up of time;Adverse reaction rate; | — |
Countries
China
Contacts
Public ContactWeifeng Shan
Lishui People's Hospital
Outcome results
None listed