Skin improvement
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Healthy women aged 35 to 45; BMI 18.5-27.9 kg/m2; (2) Wrinkle severity rating scale (WSRS) score = 2; (3) According to Fitzpatrick Pathak's skin solar reactivity, it was classified as ? - ?; (4) Sign the informed consent form voluntarily; (5) The facial skin is basically intact without ulceration and exudation; (6) No invasive treatment, laser photo cosmetology or similar treatment was used on the face 3 months before the intervention; (7) No systemic oral or intramuscular injection of glucocorticoids, collagen, hyaluronic acid and other beauty drugs and health products 3 months before the intervention; (8) There was no significant change in lifestyle, including diet and skin care during the intervention period as before; (9) During the intervention, do not use any cosmetics, drugs and health products that have an impact on the results; (10) The regularity of life can be maintained during the intervention.
Exclusion criteria
Exclusion criteria: (1) Pregnant, pregnant, lactating and menopausal women; (2) Acute anaphylaxis period or anaphylaxis to test and control substance; (3) Patients with skin diseases (such as eczema, acne, psoriasis, etc.) or obvious redness, swelling and tattoos near the test area; (4) He is receiving medication or physical therapy in recent 3 months; (5) Subjects with severe primary diseases such as severe cardiovascular, cerebrovascular, hepatorenal and hematopoietic systems, and psychiatric disorders; (6) Take contraceptives now or in the last three months; (7) Take antibiotics now or in the last three months; (8) Being involved in other clinical trials; (9) Irregular work and rest; (10) The researcher thinks it is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial spots;facial wrinkle;Facial texture;Skin color and complexion homogeneity;Skin moisturizing; | — |
Countries
China
Contacts
Fu Xing Hospital Ethics Committee