The use of opioid-free anesthesia for medium to small-sized surgery
Conditions
Interventions
Control group:Opioid drugs anesthesia
S-KTM Group:opioid-free anesthesia,S-ketamine and other narcotic drugs were used for anesthesia
Sponsors
The Affiliated Hospital of Qingdao University,Qingdao,China
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The age range is between 18 and 65 years old 2.undergo small to medium sized surgery,ASA1-3 grade 3.Patients participate voluntarily
Exclusion criteria
Exclusion criteria: 1.Allergies to study medications 2.ASA>grade3 3.Pregnancy and lactation 4.History of motion sickness 5.History of drug addiction, history of chronic pain, history of chronic opioid use (daily opioid use >3 months 6.Chronic kidney disease (serum creatinine >200µmol dl-1) 7. Subjects with known allergies or adverse reactions to S-ketamine, ketamine, patients with a history of mental illness such as mania or depression, or those with speech disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of postoperative nausea and vomiting (PONV) and?rescue treatment;Postoperative respiratory;pain condition and rescue treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative exhaust time;Inpatient Length of Stay;Adverse reactions; | — |
Countries
China
Contacts
Public ContactWei Feng
The Affiliated Hospital of Qingdao University,Qingdao,China
Outcome results
None listed