Pulmonary nodule
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1, Age = 65 years. 2, high-resolution chest CT showing multiple pulmonary nodules in different lobes of the ipsilateral lung or in different lobes of the bilateral lung, with clinical diagnosis of simultaneous multiple primary lung cancer after assessment of the clinical and imaging features of the lung nodules by a thoracic surgeon, with reference to the Martini-Melamed criteria for the diagnosis of multiple primary lung cancer. 3. the lung nodules were resectable after tumor staging examination and evaluation by a thoracic surgeon, each lung nodule was individually staged, and the clinical stage was stage I-IIIa, eligible for surgery. 4. preoperative systemic organ function assessment indicated that the patient could tolerate thoracoscopic pulmonary resection and percutaneous pulmonary ablation. 5. the patient voluntarily participated in this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pulmonary lesions were diagnosed as benign. 2 Pulmonary lesions were diagnosed as small cell lung cancer. 3, The co-existence of malignancy of other organs, or a previous history of other malignancies 4. pulmonary nodules were diagnosed as metastatic lung cancer rather than multiple primary lung cancers after the assessment by a thoracic surgeon 5 After completion of tumor staging examination, the pulmonary lesions were assessed by the thoracic surgeon as unresectable with clinical stage IIIb-IV. 6? Due to the combination of pleural cavity adhesions, chest wall deformities and other factors, the pulmonary lesion is not amenable to thoracoscopic pneumonectomy and requires direct open thoracotomy. 7, The patient has undergone previous thoracic surgery such as pneumonectomy, lung ablation, chest wall surgery, sternal or rib surgery 8, the patient has received previous treatment such as chest radiotherapy, chemotherapy, targeted therapy, etc. 9. the preoperative systemic organ function assessment shows that the patient has contraindications to anesthesia or surgery and is unable to tolerate pneumonectomy or percutaneous lung ablation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical feasibility;Perioperative;Postoperative changes in respiratory function;Surgery-related quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oncological outcome; | — |
Countries
China
Contacts
Beijing Hospital