rheumatoid arthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Female patients who meet the diagnostic criteria for RA and RA complications(carotid atherosclerosis, ILD, OP, AIH, MCI, depression, anxiety and thyroid dysfunction); (2) Aged above 18 years old; (3) Long-term residence in the community where the project is implemented (more than five years); (4) Those who can cooperate to complete the collection of relevant medical history and have complete data; (5) Sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1)Those who cannot complete the cohort study due to other primary diseases; (2)Primary diseases that affect the outcome judgment, such as ankylosing spondylitis, lupus erythematosus, psoriatic arthritis and other autoimmune diseases; (3)Patients with mental disorders such as cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| death rate;survival time;incidence of RA in this corhort; | — |
Secondary
| Measure | Time frame |
|---|---|
| total cholesterol;triglyceride;High-density lipoprot;Low density lipoprote;glycosylated hemoglobin;Fasting blood glucose;Pulmonary function;Ca;phosphorus;alkaline phosphatase, ALP;osteocalcin;25-hydroxy-vitamin D;glutamic-pyruvic transaminase, ALT;Glutamic transaminase, AST;CGT;antinuclear antibodies, ANA;Abdominal ultrasound;Thyroid ultrasound;TT3;TT4;TRAb;TPOAb;TGAb;thyroid-stimulating hormone, TSH;Carotid artery ultrasound;HRCT;Bone mineral density;Hamilton anxiety scale ( HAMA);Hamilton Depression Rating Scale, HAMD;FT3;FT4; | — |
Countries
China
Contacts
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine