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The mechanism and the effect of subchondral bone on cartilage degeneration in postmenopausal osteoarthritis

The mechanism and the effect of subchondral bone on cartilage degeneration in postmenopausal osteoarthritis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069046
Enrollment
Unknown
Registered
2023-03-06
Start date
2023-03-06
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Osteoarthritis group, OA:N/A

Sponsors

Peking University 3rd Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
55 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Corresponding to standards for TKA; 2) Corresponding to diagnosis standards for postmenopausal osteoporosis; 3) Female patients aged 55 to 75 years; 4) Patients voluntarily take part in clinical trials and sign informed consent

Exclusion criteria

Exclusion criteria: 1) Patients with neurodegenerative disease induced-myasthenia; 2) Patients with Infectious Diseases, active tuberculosis and hemorrhagic disorders; 3) Patients with activity limitation; 4) Patients with joint fibrosis, ankylosis, and activity;

Design outcomes

Primary

MeasureTime frame
Connective tissue growth factor, CTGF;

Countries

China

Contacts

Public Contactleng Huijie

Peking University Third Hospital

lenghj@bjmu.edu.cn15911118819

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026