An observational study of menstruation-related platelet function in healthy women of childbearing age

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300069043

Enrollment

Unknown

Registered

2023-03-06

Start date

2023-03-06

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group of healthy female volunteers:No

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Healthy women with regular periods (21-35 days, 2-7 days); 2. Age =18 years old and =35 years old; 3. Volunteer to take the test and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with menstrual disorders in the last three months (low menstrual cycle, abnormal uterine bleeding, intermenstrual bleeding, menorrhagia, amenorrhea, irregular menstruation sequence, etc.); 2. Those who plan to become pregnant or during pregnancy or lactation; 3. Have a history of abortion in the past six months (medical abortion or surgical abortion); 4. Have taken antiplatelet drugs (aspirin, clopidogrel, ticagrelor, acximab, etc.), anticoagulant drugs (heparin, rivaroxaban, warfarin, etc.) or other drugs that may affect platelet function in the past three months, including Chinese patent medicine or decoction of HuoxueHuayu; 5. Used birth control pills (including oral, topical and subcutaneous injections) within the last three months; Placement of intrauterine devices; 6. Diagnosis of hypertension, dyslipidemia, liver or kidney diseases, endocrine and gynaecological diseases, mental disorders and a history of chronic diseases; 7. Thrombotic disease, hemorrhagic disease or bleeding tendency; 8. Patients with infection or allergic symptoms at the time of blood sample collection and regular vigorous exercise (exercise time exceeding 1 hour/time, average heart rate during exercise reaching 140 times /min or above, exercise times =3 times/week); 9. Anemia patients (hemoglobin 300×10^6/L); 10. Those who have a history of smoking or are still smoking; Those who drink more than 35g pure alcohol per day, that is 2 drinks per day (1 drink =150ml red wine or 360ml beer or 50ml white wine); 11. Participants in other clinical trials.

Design outcomes

Primary

Measure	Time frame
Platelet activation rate;	—

Secondary

Measure	Time frame
Platelet aggregation test;Coagulation function;	—

Countries

China

Contacts

Public ContactMIngjie Zi

Xiyuan Hospital, China Academy of Chinese Medical Sciences

drzimingjie@126.com13621052996

Outcome results