peri-implant disease
Conditions
Interventions
experimental group :glycine subgingival air polishing
Control group:N/A
Peri-implant health group:N/A
Peri-implant mucositis group:N/A
Peri-implant inflammation group:N/A
Sponsors
Department of Periodontology, Peking University School and Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Part One of the Study Participants of the study: Patients who underwent jaw reconstruction surgery due to tumors in the Department of Oral and Maxillofacial Surgery at Peking University School and Hospital of Stomatology and completed implant restoration between January 2020 and December 2022. Inclusion criteria: 1. Age: 18-70 years old. 2. Implants in the jaw reconstruction area using either fibula or iliac crest graft have completed restoration for at least 3 months. Part Two of the Study Participants of the study: Patients who underwent jaw reconstruction surgery due to tumors in the Department of Oral and Maxillofacial Surgery at Peking University School and Hospital of Stomatology and completed implant insertion between January 2023 and December 2024. Inclusion criteria: 1. Age: 18-70 years old. 2. Implants in the mandibular reconstruction area using either fibula or iliac crest graft have been inserted for 3 months. 3. Radiographs show the implant has good osseointegration, and the bone absorption around the implant is less than half of the implant length.
Exclusion criteria
Exclusion criteria: Part One of the Study Exclusion criteria: 3. Refusing to participate in the study. 4. Having Received radiation or chemotherapy, or being unable to complete follow-up treatment due to disease recurrence. 5. Having Received mechanical debridement or antibiotic treatment in the past three months. 6. Heavy smoker (more than 10 cigarettes per day). 7. Suffering from systemic diseases such as uncontrolled diabetes or hypertension, upper respiratory tract infection. Part Two of the Study Exclusion criteria: Same as Part One.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| probing depth;bleeding index;inflammatory cytokine level in peri-implant crevicular fluid;Bacterial diversity of peri-implant plaque; | — |
Secondary
| Measure | Time frame |
|---|---|
| modified plaque index;keratinized mucosa width;mucosal thickness;marginal bone loss; | — |
Countries
China
Contacts
Public ContactLu Ruifang
Peking University School and Hospital of Stomatology
Outcome results
None listed