Study on immune responses and early warning model of severe abdominal candidiasis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300069020

Enrollment

Unknown

Registered

2023-03-03

Start date

2023-03-03

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe abdominal candidiasis

Interventions

Group of severe abdominal candidiasis:None

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: ? Age = 18 years old; ? Expected length of stay in ICU = 48h; ? Abdominal infection, and also meets the sepsis 3.0 definition standard of the American Society of Critical Care Medicine/European Society of Critical Care Medicine (SCCM/ESICM) in 2016, that is, fatal organ dysfunction caused by infection (sequential (infection-related) organ failure score SOFA = 2), or the need for vasopressor drugs to maintain mean arterial pressure = 65mmHg and blood lactate level>2mmol/L after full fluid resuscitation.

Exclusion criteria

Exclusion criteria: ? Age<18; ? Pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
Lymphocyte subtyping;	—

Secondary

Measure	Time frame
IL-6;IL-8;TNF;Immunoglobulin;CRP;PCT;(1,3)-ß-D-glucan;	—

Countries

China

Contacts

Public ContactJiahui Zhang

Peking Union Medical College Hospital

zhangjiahui_1222@163.com+86 13439973903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026