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Remimazolam versus propofol sedation on the quality of recovery in patients with painless induced abortion :A randomized non-inferiority trial

Remimazolam versus propofol sedation on the quality of recovery in patients with painless induced abortion :A randomized non-inferiority trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069017
Enrollment
Unknown
Registered
2023-03-03
Start date
2023-03-01
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Sponsors

Mindong Hospital Affiliated to Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing elective, painless induced abortion surgery (2) Age 18-45 years; (3)BMI18~28kg/m2 (4) Gestation time, 50-75 days; (5) Blood routine, coagulation routine, urine routine, white ribbon routine, liver and kidney function test results were unremarkable; (6) American Society of anesthesiologists (ASA) class I to II; (7) Informed of the experimental procedure and risks of anaesthesia, volunteered to participate in this study and signed consent for anaesthesia.

Exclusion criteria

Exclusion criteria: ?Patients with severe respiratory diseases; ?Patients with respiratory tract management difficulties:Modified Mallampati Score=III; ?HR<50 times/min,Atrioventricular block,Etc.Patients with severe arrhythmia; ?Patients with uncontrolled hypertension, hypotension and diabetes; ?Patients with severe liver and kidney dysfunction ?Patients with known or suspected allergy to propofol inj, benzodiazepines; ?Patients with alcoholism, drug abuse and chronic use of narcotic sedatives, narcotic analgesics, etc; ?Patients with mental illness ?Patients who have participated in clinical trials of any drug within 3 months; ?The investigator felt that there were any other conditions that were not suitable for participation in this study

Design outcomes

Primary

MeasureTime frame
Postoperative quality of recovery-15;

Secondary

MeasureTime frame
Incidence of nausea and vomiting after awakening;Injection pain;Time to discharge;Incidence of hypoxemia;Incidence of hypotension;The number and frequency of additional sedative drugs;Recovery time;

Countries

China

Contacts

Public ContactDigui Weng

Mindong Hospital Affiliated to Fujian Medical University

wdgmdyy813@163.com13706930791

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026