Endoscopic therapy
Conditions
Interventions
Fentanyl combined with propofol (Group F):the main anesthesia drugs are fentanyl and propofol
Esketamine combined with propofol (Group E):the main anesthesia drugs are esketamine and propofol
Sponsors
Zhongshan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: ? Older than 18 years old ? Endoscopic therapy under colonoscopy is planned ? ASA class I-III ? Sign informed consen
Exclusion criteria
Exclusion criteria: ? Allergy to known narcotic drugs ? Uncontrolled hypertension or hypertensive crisis ? Ischemic heart disease ? Mental illness ? Taking analgesics for a long time due to chronic pain ? Pregnant or lactating women ? Drug abuse ? Epilepsy ? Intracranial hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total propofol dosage in each group; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure change;oxygen saturation;Heart rate;Respiration rate;Incidence of sedatin-related adverse events;Utilization rate of vasoactive drugs;Onset of effective;Awake time;Satisfaction of the operator with anesthesia;Satisfaction of the patient with anesthesia;Occurrence of postoperative adverse events;The occurrence of a postoperative undesirable mental state; | — |
Countries
China
Contacts
Public ContactYao Minmin
Outcome results
None listed