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Efficacy of enhanced external counterpulsation in preventing contrast-induced acute kidney injury after primary percutaneous coronary intervention in acute ST-segment elevation myocardial infarction -based on cystatin C

Efficacy of enhanced external counterpulsation in preventing contrast-induced acute kidney injury after primary percutaneous coronary intervention in acute ST-segment elevation myocardial infarction -based on cystatin C

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069005
Enrollment
Unknown
Registered
2023-03-03
Start date
2023-03-20
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

contrast-induced acute kidney injury

Interventions

EECP group:enhanced external counterpulsation treatment
control group:conventional therapy

Sponsors

Yulin First People’s Hospital(The Sixth Affiliated Hospital of Guangxi Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ? Age = 18 years and<80 years; ? Meet STEMI diagnostic criteria, and the time from onset to hospital arrival is within 12h; ? Complete primary PCI; ? Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Iodine contrast agent was used 30 days before enrollment; 2.Acute renal damage caused by other definite causes; 3.Uncontrolled blood pressure (> 180/110mmHg); 4.Uncontrolled arrhythmias, including tachycardia (>120 beats/min), bradycardia ( 3.0; 10.Severe skin damage, infection or fracture of lower limbs; 11.Moderate to severe pulmonary hypertension (mean pulmonary artery pressure>50mmHg); 12.Pacemaker implantation; 13.Hemodialysis or peritoneal dialysis; 14.Mechanical complications such as cardiac thrombosis, perforation, papillary muscle rupture; 15.Femoral artery puncture; 16.Hip replacement or femoral head surgery or severe lumbar disc herniation; 17.Pregnancy.

Design outcomes

Primary

MeasureTime frame
cystatin C;

Secondary

MeasureTime frame
Serum creatinine;estimated glomerular filtration rate;ß 2 microglobulin;Retinol protein;all cause death;Composite endpoint of all-cause death and major cardiovascular events;

Countries

China

Contacts

Public ContactChun-Mei Zeng

Yulin First People’s Hospital(The Sixth Affiliated Hospital of Guangxi Medical University)

876757972@qq.com18276509284

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026