severe acute pancreatitis with acute respiratory distress syndrome
Conditions
Interventions
Neuromuscular electrical stimulation group:Standard care + neuromuscular electrical stimulation
Control group:Standard care
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years; 2. The patient was admitted to ICU >=24h, and was diagnosed with severe acute pancreatitis combined with acute respiratory distress within 48 hours of admission (meeting the diagnostic criteria for severe acute pancreatitis and acute respiratory distress at the same time); 3. Sign informed consent; 4. Those who are willing to accept the treatment of the test method and voluntarily complete the course of treatment.
Exclusion criteria
Exclusion criteria: 1. Unable to walk independently before the onset of the disease; 2. Cognitive dysfunction before the onset of the disease; 3. Previous neuromuscular diseases (such as severe muscular atrophy, amyotrophic lateral sclerosis, myasthenia gravis); 4. Severe fracture, spinal cord injury, deep vein thrombosis and other conditions requiring braking; 5. Estimated duration of onset over 7 days and completion of treatment in ICU of other hospitals; 6. Pregnancy; 7. Death is estimated within 24 hours; 8. Terminal stage of malignant tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Medical Research Council (MRC) Scale for Muscle Strength;Grip;Thigh circumference;Calf circumference; | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute Physiology and Chronic Health Evaluation II Score;Sequential Organ Failure Assessment (SOFA);Marshall Score;Barthel Score;Diaphragm thickness;Changes in diaphragm thickness;Length of ICU stay;Total cost of hospitalization; | — |
Countries
China
Contacts
Public ContactFan Dingrong
The Second Affiliated Hospital of Chongqing Medical University
Outcome results
None listed