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HMGB1/airway microecology as a predictor of long-term recurrent wheezing in children with RSV infection

HMGB1/airway microecology as a predictor of long-term recurrent wheezing in children with RSV infection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300068992
Enrollment
Unknown
Registered
2023-03-03
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiolitis

Interventions

Observation group:None
Control group:N/A

Sponsors

Chengdu Women's and Children's Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 2 Years

Inclusion criteria

Inclusion criteria: 1. Research group: children with bronchiolitis within 2 years old who were admitted to the respiratory department of our hospital from October 2022 to October 2023 with positive RSV detection. 2. Control group: children with non respiratory tract and intestinal tract infection hospitalized due to surgical operation at the same time and age.

Exclusion criteria

Exclusion criteria: Infants with congenital heart disease, immunodeficiency, bronchopulmonary dysplasia, cystic fibrosis, neuromuscular disease, inherited metabolic disease, and chromosomal disorders.

Design outcomes

Primary

MeasureTime frame
High Mobility Group Protein B1, HMGB1;Airway Microbial Composition;—

Countries

China

Contacts

Public ContactTang Wei

Chengdu Women's and Children's Central Hospital

tangw623@126.com+86 136 5766 9270

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026