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Study on the mechanism of acupuncture treatment of premature ovarian insufficiency based on transcriptome sequencing technology

Study on the mechanism of acupuncture treatment of premature ovarian insufficiency based on transcriptome sequencing technology

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068981
Enrollment
Unknown
Registered
2023-03-03
Start date
2023-03-03
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premature ovarian insufficiency (POI)

Interventions

Experimental group:Acupuncture
Control group:None

Sponsors

Shenzhen Maternity and Child Healthcare Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
19 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1. According to the Guideline of the European Society of Human Reproduction and Embryology, it conforms to the diagnosis of premature ovarian insufficiency in western medicine; 2. Women of childbearing age under 40 years old; 3. Sporadic menstruation or amenorrhea >=4 months; 4. FSH>25IU/L (at least 2 times, and the interval between 2 times is more than 1 month); 5. Agree to receive treatment and follow up observers according to this protocol; 6. Willing to sign informed consent; 7. Willing to register cases.

Exclusion criteria

Exclusion criteria: 1. Patients with ovariectomy; 2. Have a history of radiotherapy or chemotherapy; 3. Have urethral infection or tumor; 4. Have autoimmune diseases; 5. Abnormal birth reproductive organs; 6. Complicated with serious primary diseases of cardiovascular, kidney, liver and hematopoietic system; 7. Intellectual behavior disorder, unable to cooperate with clinical observation.

Design outcomes

Primary

MeasureTime frame
sex hormone;anti-Müllerian hormone;

Secondary

MeasureTime frame
transcriptome sequencing;

Countries

China

Contacts

Public ContactWu Jiaman

Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University

wujiaman202@163.com+86 158 1747 0407

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026