None listed
Conditions
Interventions
Experimental group:Radiofrequency thermocoagulation using intracranial brain electrodes for epilepsy treatment at once
Sponsors
Beijing Tiantan Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
8 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. No gender limit, aged 8-60 years; 2. Previously diagnosed as drug-resistant epilepsy; 3. Patients who have no less than one seizure per month; 4. Patients who plan to undergo stereotactic electroencephalogram monitoring and surgical treatment; 5. Those who have not participated in other clinical trials within three months; 6. The patient or his/her guardian can understand the purpose of the experiment, comply with the experiment protocol, participate voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe coagulation dysfunction; 2. Allergic to electrode materials; 3. Patients with pacemakers or other active implants; 4. Patients with contraindications of neurosurgery and serious cardiovascular and cerebrovascular diseases; 5. Systemic diseases that seriously affect health, such as severe abnormal liver and kidney function; 6. Patients who are pregnant or have pregnancy intention in recent half a year, or lactating patients; 7. Patients deemed unsuitable for clinical trials by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency of seizures at 84 days after surgery was compared with baseline to verify that the effective rate of thermocoagulation treatment for epilepsy met the preset target value;Verify that the diameter of the short shaft of the thermal coagulation damage range meets the preset target value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of electrode implantation;Immediate success rate of thermocoagulation;Electroencephalogram changes before and after thermocoagulation;The performance of the device was evaluated by the investigators; | — |
Countries
China
Contacts
Public ContactZhang Kai
Beijing Tiantan Hospital Affiliated to Capital Medical University
Outcome results
None listed