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Validation of very-early cell markers of gastric cancer in retrospective longitudinal cohorts of gastritis-induced tumorigenesis

Clinical sequential sample validation of cell markers in the very early stage of gastric cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300068967
Enrollment
Unknown
Registered
2023-03-02
Start date
2021-03-09
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Precursors of gastric cancer

Interventions

Progression group:None
Regression group:None
Persistence group:None

Sponsors

Tsinghua University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Low grade intraepithelial neoplasia was diagnosed at baseline; 2. At least two endoscopic monitoring records; 3. The endoscopic monitoring period should be at least 3 months; 4. The lesion was located in the gastric antrum.

Exclusion criteria

Exclusion criteria: 1. Low-grade heterotrophic hyperplasia was the case at the last time point. 2. Cases with too small pathological tissue and other cases that do not meet the requirements of clinical supplementary pathological detection. 3. The baseline diagnosis is accompanied by gastric ulcers or gastric polyps. 4. History of surgical intervention.

Design outcomes

Primary

MeasureTime frame
Detection rate of the patient group of progression to gastric cancer;—

Secondary

MeasureTime frame
Duration of progression of gastric cancer;—

Countries

China

Contacts

Public ContactLi Shao

Tsinghua University

shaoli@mail.tsinghua.edu.cn+86 10 62797035

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026