obesity
Conditions
Interventions
Control group:Implement lung-protective ventilation strategies according to the clinical experience of the attending anesthesiologist
Real-time B-ultrasound group:Implement lung-protective ventilation strategies according to the results of lung ultrasonography
Real-time EIT group:Implement lung-protective ventilation strategies according to EIT results
Sponsors
Ji'nan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with body mass index (BMI) >=40 kg/m^2 without severe obesity-related complications; 2. Patients with a body mass index (BMI) >=35 kg/m^2 and one or more severe obesity-related complications that can be corrected by bariatric surgery; 3. Patients with a body mass index (BMI) of 28-34.9 kg/m^2 and poorly controlled metabolic syndromes such as type 2 diabetes and/or arterial hypertension despite optimal lifestyle and medication; 4. Patients aged 18-65 years agreed to participate in the study with full understanding.
Exclusion criteria
Exclusion criteria: 1. Patients who lose the ability to perform daily life; 2. Patients during pregnancy or breastfeeding; 3. Patients with severe liver and kidney insufficiency, cardiopulmonary insufficiency, or other serious diseases who have not received standard treatment before surgery; 4. Patients with serious mental illness in the past; 5. Patients in the active stage of tumor; 6. Patients with poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of perioperative hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| the content of inflammatory factors in gastric mucosa;pH of gastric juice;incidence of postoperative pneumonia;partial expiratory time constant;regional ventilation delay inhomogeneity;silent spaces;regional respiratory system compliance;global inhomogeneity;center of ventilation;impedance ratio;end-expiratory lung impedance;tidal impedance variation;arterial partial pressure of oxygen;arterial carbon dioxide partial pressure;pH of arterial blood; | — |
Countries
China
Contacts
Public ContactWang Hao
Ji'nan University
Outcome results
None listed