Skip to content

Study on the mechanism of acupuncture-knee intervention based on dual-task walking in the brain network mechanism of post-stroke cognitive impairment

Study on the mechanism of acupuncture-knee intervention based on dual-task walking in the brain network mechanism of post-stroke cognitive impairment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068950
Enrollment
Unknown
Registered
2023-03-02
Start date
2023-04-06
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Part I: Health Group:Single task walking
Simple dual task walking
Complex dual-task walking
Part I: High Cognition Group:Single task walking
Part I: Low Cognition Group:Single task walking
Part II: Control subjects:Routine Gait Training
Part II: Cognitive dual-tasking group:Cognitive Gait Training
Part II: Acupuncture and moxibustion therapy group:Cognitive walking training combined with cephalic needle plexus

Sponsors

The Third Hospital of Zhejiang University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Part I: 1. low cognitive group: (1) Meets diagnostic criteria for ischaemic stroke or haemorrhagic stroke. (2) Have a CDR score of 0.5 and a completely normal or mildly impaired ability to live and work. (3) Have the ability to walk independently. (4) Be male or female between the ages of 18 and 85 years. (5) Duration of ischaemic or haemorrhagic stroke between 1 and 6 months. (6) Patients signed an informed consent form and cooperated with the intervention. 2. Highly cognitive group: (1) Meet the diagnostic criteria for ischaemic stroke or haemorrhagic stroke. (2) Have a CDR score of 0 and a completely normal life and work capacity. (3) Ability to walk independently. (4) Male or female aged 18 to 85 years. (5) Duration of ischaemic or haemorrhagic stroke between 1 and 6 months. (6) Patients signed an informed consent and cooperated with the intervention. 3. Healthy group: (1) No organic neurological lesions. (2) CDR score of 0. (3) No disease affecting walking, such as osteoarthritis of the knee or ankylosing spondylitis. (4) Male or female aged between 18 and 85 years old. (5) Signed informed consent and co-operated with the intervention. Part II: As with the "Low Cognitive Group" in Part 1, participants will be randomised to the Cognitive Dual Task Group, the Acupuncture Group, and the Control Group.

Exclusion criteria

Exclusion criteria: 1. Impairment of consciousness, severe visual, hearing, and speech impairments, and inability to complete other health assessments. 2. The presence of brain diseases of other nature (e.g., multiple sclerosis, brain tumors) and other diseases that restrict gait (e.g., fractures, amputations). 3. Cognitive impairment from other causes, such as Alzheimer's disease (AD) and dementia with Lewy bodies. 4. Accompanying medical conditions, such as depression, psychotic symptoms, and a history of alcohol, drug abuse, or dependence. 5. Failure to follow research procedures. 6. Aphasia or other disorders that affect pronunciation. 7. Complicated with tumors, serious diseases of organs and endocrine system.

Design outcomes

Primary

MeasureTime frame
Cerebral oxyhemoglobin;Cerebral deoxyhemoglobin;

Secondary

MeasureTime frame
Gait-related indicators;Correct counting rate;

Countries

China

Contacts

Public ContactChen Jing

The Third Hospital of Zhejiang University of Traditional Chinese Medicine

doctorchen1975@163.com+86 151 1456 4282

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026