Colorectal tumours
Conditions
Interventions
Intertransverse block group (ITP group):Patients with bilateral intertransverse block
Thoracic paravertebral block group (TPVB group):Patients with bilateral thoracic paravertebral blocks
Sponsors
Shanghai Jiaotong University Affiliated Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with colorectal tumor and intended to undergo laparoscopic colorectal surgery; 2. Aged 18-65 years; 3. Sign informed consent; 4. American Society of Anesthesiologists (ASA) grade I-II.
Exclusion criteria
Exclusion criteria: 1. Any relevant major heart or respiratory disease, hematological disease or disorder of coagulation parameters, preexisting major organ dysfunction (e.g., liver or kidney failure); 2. General contraindications of nerve block; 3. Any contraindications for the use of propofol, sufentanil, or sevoflurane; 4. Patients with a history of laparotomy; 5. Patients with previous somatosensory disorders; 6. Patients with spinal anatomic malformations; 7. Patients undergoing emergency surgery; 8. Patients with a long history of opioid use; 9. Patients with mental illness or inability to understand the NRS score.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 12 hour post-operative motor pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blocking success rate;Numeric rating scale for patient's resting state and cough;Plasma vascular endothelial growth factor-C, IL-6, epinephrine and cortisol levels at 24 hours postoperatively;Degree of nausea and vomiting;Total intra-operative opioid use and total post-operative opioid use;Time to first bowel sounds, time to intestinal exhaust, time to return to activity, and length of hospital stay;Incidence of nerve block-related complications;Quality of patient recovery; | — |
Countries
China
Contacts
Public ContactGu Fei
Shanghai Jiaotong University Affiliated Sixth People's Hospital
Outcome results
None listed