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Changes of brain functional connectivity before and after treatment in patients with chronic insomnia disorder and its correlation with clinical features

Changes of brain functional connectivity before and after treatment in patients with chronic insomnia disorder and its correlation with clinical features

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068927
Enrollment
Unknown
Registered
2023-03-01
Start date
2023-03-01
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic insomnia disorder

Interventions

Group of chronic insomnia disorder:drug therapy
Healthy control group:none

Sponsors

The Second Affiliated Hospital of Xinxiang Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for patients with chronic insomnia disorder: (1) CID diagnostic criteria of International Classification of Sleep Disorders, 3rd edition, ICSD-3 were met; (2) Aged 18-60 years, right-handed; (3) Junior high school or above; (4) Pittsburgh Sleep Quality Index score more than 7 (PSQI score > 7). 2. Inclusion criteria of healthy controls: (1) Age, sex and years of education were matched with chronic insomnia disorder patients; (2) Good sleep quality and PSQI score <=7.

Exclusion criteria

Exclusion criteria: 1. Sleep disorders other than CID (based on ICSD-3 criteria); 2. Hamilton Depression Scale score >=18 and Hamilton Anxiety Scale score >=14; 3. Serious diseases of the heart, cerebrovascular, liver, kidney or hematopoietic system; 4. Any contraindications to MRI scans with pacemakers, nerve stimulators, artificial metal heart valves, etc., and claustrophobia, etc.; 5. History of mental or neurological disorders or head trauma with loss of consciousness; 6. Pregnant, pregnant, nursing patients.

Design outcomes

Primary

MeasureTime frame
Functional brain imaging;

Countries

China

Contacts

Public ContactXu Yahui

The Second Affiliated Hospital of Xinxiang Medical College

18737354427@163.com+86 18567389001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026