Gastric cancer
Conditions
Interventions
group of patients with gastric cancer undergoing preoperative chemotherapy:NA
Sponsors
China Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Patient has given informed consent; 2.Aged >= 18 years; 3.Patient has been diagnosed with gastric adenocarcinoma through histopathological biopsy and has available pathological WSI (Whole Slide Imaging); 4.Underwent standardized contrast-enhanced abdominal CT scan prior to neoadjuvant chemotherapy; 5.Diagnosed with locally advanced gastric cancer through contrast-enhanced abdominal CT scan, with infiltration beyond the submucosa and no distant metastasis; 6.No previous gastric surgery; 7.No history of other malignancies before neoadjuvant treatment; 8.No anti-tumor treatment before the contrast-enhanced abdominal CT scan; 9.No mental disorders or cognitive impairment.
Exclusion criteria
Exclusion criteria: 1.Receiving neoadjuvant chemotherapy regimens other than XELOX and SOX; 2.Did not undergo radical surgery after neoadjuvant chemotherapy; 3.Postoperative pathological TRG (Tumor Regression Grade) is unknown; 4.Poor quality of CT images (due to insufficient gastric filling or artifacts) or poor quality of WSI (Whole Slide Imaging); 5.Perioperative death.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor regression grade;Efficacy evaluation criteria for solid tumors (RECIST 1.1); | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival;event-free survival; | — |
Countries
China
Contacts
Public ContactWang Zhenning
The First Hospital of China Medical University
Outcome results
None listed