Hernia, hydrocele, cryptorchidism and other diseases
Conditions
Interventions
Control group:0.7MAC desflurane combined with remifentanil 10µg/(kg/h) was used to maintain anesthesia
Experimental group A:Dexmedetomidine 1µg/kg was intravenously injected before anesthesia induction, and 0.7MAC desflurane combined with 0.5µg/(kg/h) dexmedetomidine was used to maintain anesthesia
Experimental group B:Dexmedetomidine 1µg/kg was intravenously injected before anesthesia induction, and desflurane 1MAC combined with dexmedetomidine 0.5µg/(kg/h) was used for anesthesia maintenance
Experimental group C:Dexmedetomidine 1µg/kg was administered intravenously before induction of anesthesia, and desflurane 1MAC was used for maintenance of anesthesia
Experimental group D:Dexmedetomidine 1µg/kg was administered intravenously before induction of anesthesia, and 1.3MAC desflurane was used for maintenance of anesthesia
Sponsors
Department of Anesthesiology, the Sixth Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
5 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. ASA grade ?-?; 2. BMI<=30 (kg/m^2); 3. Aged between 5 and 12 years; 4. Children undergoing laparoscopic surgery; 5. The operation time is less than two hours.
Exclusion criteria
Exclusion criteria: 1. Patients with high risk of perioperative respiratory adverse events (recent history of upper respiratory tract infection, abnormal chest radiographs or abnormal blood images, malformation or dysplasia of respiratory tract or lung organs); 2. Patients with abnormal liver and kidney function or congenital heart disease; 3. Pneumoperitoneum intolerance; 4. Obvious mental retardation; 5. Suspected allergy to the drug in the study; 6. There are contraindications to regional block (abnormal coagulation status, hemorrhagic disease, local infection, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic measures;Indicators of early recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Indicators of adverse events in postoperative PACU;Indicators of health economic benefits; | — |
Countries
China
Contacts
Public ContactYang Wanchao
Department of Anesthesiology, the Sixth Affiliated Hospital of Harbin Medical University
Outcome results
None listed