adenomyosis
Conditions
Interventions
1:Ultra-long GnRHa protocal
2:Long GnRHa protocol
Sponsors
Shanghai First Maternal and Infant Health Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: A 25-40 years old; B patients with adenomyosis with uterine volume <12 gestational weeks or adenomyoma <6cm; C was clinically diagnosed as uterine adenomyosis, in line with IVF indications, including fallopian tube factors, ovulation disorders, endometriosis, 3 artificial insemination failures and male factors, etc.; D Diagnosis of adenomyosis: According to the 2021 Chinese expert Consensus on the Diagnosis and Treatment of adenomyosis with Infertility (13) (Chinese Journal of Reproduction and Contraception, April 2021), the 2018 Federation International of Gynecology Anti is recommended The moqthological Uterus Sonographic Assessment (MUSA) was developed by the Obstetrics (FIGO) Team for the diagnosis of adenomyosis based on TVUS imaging. A total of 8 ultrasonographic features were asymmetric thickening of uterine muscularis. Myometrium cystic foci; Island high echo signal; Fan shadow; Linear or punctate echo under endometrium; There were striped blood flow signals passing through the lesion. The morphology of the binding zone is irregular; The band is discontinuous, and the evaluation of the band is recommended to be confirmed by 3D-TYUS examination. Adenomyosis should be diagnosed if 2 or more of these signs are present on ultrasound.
Exclusion criteria
Exclusion criteria: A uterine volume >=12 gestational weeks or adenomyoma >=6cm B systemic diseases of the whole body; C. Pre-implantation embryo genetic diagnosis cycle, egg donation cycle, egg freezing cycle, sperm supply cycle; D hyperprolactinemia, ovarian tumor; Uterine malformation (double uterus, mediastinal uterus, etc.); E patients with hydrosalpinx or untreated endometrial polyp; F Patients with acute and chronic genital tract tumors, genital tract inflammation and other diseases that are not suitable for ovulation promotion; G Patients receiving hormone therapy within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| uterine size;adenomyosis size;CA125;number of eggs retrieved;Cumulative live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| complication of pregnancy;miscarriage rate;Embryo implantation rate;number of normal fertilization;number of embryos avaliable;AMH;clinical pregnancy rate; | — |
Countries
China
Contacts
Public ContactAi Ai
Shanghai First Maternal and Infant Health Hospital
Outcome results
None listed