FindTrial
Sign In

Application of Tai Chi Training to Improve Postmenopausal Mild Cognitive Disorder

Study on Application of Tai Chi Training to Improve Postmenopausal Mild Cognitive Impairment Based on Neurovascular Coupling Theory

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068871
Enrollment
Unknown
Registered
2023-03-01
Start date
2023-03-01
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognitive impairment

Interventions

Health education group:To provide health education on the etiology and prevention of MCI
Tai Chi group:Carry out 60 minutes of Tai Chi training three times a week on the basis of health education

Sponsors

The Second Affiliated Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Postmenopausal women aged 50-75,who menopause for 12 months or more, and have not received chemotherapy, endocrine therapy or treatment to inhibit ovarian function, and follicular estrogen and estradiol are at postmenopausal level; 2. Meet the diagnostic criteria of MCI; 3. Theres no serious audio-visual disorders, have a certain understanding and language expression ability, and can cooperate to complete all inspections; 4. Agree to join the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Presence of stroke, brain tumor, brain injury, intracranial infection, epilepsy or other neurological diseases; 2. Suffer from serious mental illness, such as depression; 3.Have contraindications to exercise; 4.Have a history of alcohol or other drug abuse, or currently taking drugs to improve cognition; 5.Presence of serious primary diseases or malignant tumors of heart, liver, kidney, blood or endocrine system etc; 6.The regular exercise time is more than 1 hour per week 3 months before enrollment.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment score;Trail Making Test-A test time;Trail Making Test-B test time;Activities of Daily Living score;CBF in different brain regions;—

Secondary

MeasureTime frame
Body Mass Index;Systolic blood pressure(SBP);Diastolic blood pressure(DBP);Estradiol;Fasting blood glucose(FBG);Total cholesterol(TC);Triglyceride(TG);Low density lipoprotein cholesterol(LDL-C);High density lipoprotein cholesterol(HDL-C);Nitric Oxide;Prostaglandin-I2;Endothelin-1;Thromboxane A2;Total TAU protein(T-tau);Phosphorylated TAU protein(P-tau);Amyloid ß-protein1-42(Aß1-42);—

Countries

China

Contacts

Public ContactYan Zheng

The Second Affiliated Hospital of Traditional Chinese Medicine

yanzheng_2023@163.com+86 18065019690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026