paronychia
Conditions
Interventions
Metronidazole group:Metronidazole gel, topically
control group:placebo gel, topically
Sponsors
the Fifth Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1: Age 18-65 2: Clinically meet the diagnostic criteria for chronic mild paronychia, untreated 3: Voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1: Any diseases that may cause nail damage, such as psoriasis, lichen planus, etc. 2: Antibiotics or proprietary Chinese medicines or Chinese medicines with antibacterial effect taken or peripherally around the nails in the past 3 months 3: Pregnant and lactating women 4: Have severe chronic diseases such as blood system diseases, chronic renal failure, hepatic insufficiency/hepatitis, malignant tumors, autoimmune diseases, chronic inflammatory diseases (such as lupus erythematosus, scleroderma, dermatomyositis, vasculitis, inflammatory bowel disease, etc.) 5: Those who are allergic to metronidazole and any component of the gel matrix 6: Those with mental abnormalities and unrealistic fantasies about treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptoms and signs improvement percentage; | — |
Secondary
| Measure | Time frame |
|---|---|
| recurrence rate at 12W;Skin Disease Life Quality Index; | — |
Countries
China
Contacts
Public ContactHan Ma
the Fifth Affiliated Hospital, Sun Yat-sen University
Outcome results
None listed