glaucoma
Conditions
Interventions
group1:Stent assisted Liangs Internal drainage Trabecular Surgery
group2:Microcatheter-assisted circumferential trabeculotomy
Sponsors
TONGJI HOSPITAL TONGJI MEDICAL COLLEGE OF HUST
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1)aged 18 to 75 years old (2)Patients with open-angle glaucoma with glaucoma medications or not with IOP > 21 mmHg; (3)Voluntarily participate in this clinical trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) axis length 28mm; (2) BCVA of enrolled eye or contralateral eye <0.05; (3) with obvious cataract that is expected to undergo cataract surgery within 1 year (4) Patients with malignant glaucoma, active intraocular inflammation (such as uveitis glaucoma, etc.), neovascular glaucoma, glaucoma with elevated episcleral venous pressure, and glaucoma secondary to malignant tumors; (5) Patients with a condition that affects the reliability of IOP measurement such as thyroid associated ophthalmopathy; (6) Patients with a history of intraocular surgery (LPI laser iridoplasty and cataract surgery excepted) or conjunctival surgery such as gizzard excision with upper conjunctival transplant transplantation; (7)Patients with a history of allergy to anesthetic drugs or nitinol; (8)Patients with corneal dystrophy, active corneal inflammation, or ocular tumors; (9)Patients with Corneal endothelial cell density<800/mm2; (10)unable to cooperate with the examination, such as those with mental illness; (11)Pregnant and lactating women; (12)Have participated in other clinical trials within 30 days prior to this enrollment and may affect the evaluation of this clinical trial; (13)Other situations in which the investigator deemed inappropriate to participate in this trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IOP at postoperative 6 months; | — |
Secondary
| Measure | Time frame |
|---|---|
| qualified success rate at 6 months;complete success rate at 6 months;IOP reduction;number of glaucoma medications;Corneal endothelial cell loss rate;corneal thickness;uncorrected visual acuity;BCVA; | — |
Countries
China
Contacts
Public ContactHong Zhang
TONGJI HOSPITAL TONGJI MEDICAL COLLEGE OF HUST
Outcome results
None listed