colorectal cancer
Conditions
Interventions
control group:Opioid drugs
experimental group:Opioid free
Sponsors
People's Hospital of Three Gorges University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients with abdominal colon cancer or rectal cancer undergoing radical surgery; (2) Age: 40-75 years old; (3) Have the ability of independent behavior, clear awareness, and understand the investigation content; (4) Respondents agreed to participate in the study and signed the informed consent form
Exclusion criteria
Exclusion criteria: (1) Patients who are allergic to the drugs used in the study (2) Epilepsy, mental or nervous system disease, unable to cooperate with postoperative pain score (3) Chronic pain, long-term use of opiates, hormones or non-steroidal drugs (4) Hypertension patients with poor control or without treatment (resting systolic/diastolic blood pressure exceeding 180/100mmHg) (5) Serious arrhythmia. (6) Severe liver and kidney dysfunction (7) Patients with glaucoma or cerebrovascular disease, elevated intraocular pressure or intracranial pressure (8) Patient conversion to open surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15; | — |
Secondary
| Measure | Time frame |
|---|---|
| cortisol;Norepinephrine;mean arterial pressure;heart rate;Awakening time;Visual Analogue Scale VAS; | — |
Countries
China
Contacts
Public ContactXiaobo Chen
People's Hospital of Three Gorges University
Outcome results
None listed