major depressive disorder
Conditions
Interventions
trial:5 training tasks recommended by the system every day, 8 minutes each time, 40 minutes a day, 4 days a week, and the training period was 8 weeks
contrl:The lowest difficulty perceptual training task pushed by the system, such as size matching task, etc. The comfort training group maintained the same frequency and length of training as the cogn
Sponsors
Beijing Anding Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of depression (MDD) in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5); 2. MECT was required for this hospitalization, and MECT had not been performed in the previous 12 months; 3. Hamilton Depression Scale (HDRS-17) >= 17 points and ECCA score >=23 points 24h before the first MECT treatment; 4. Compared with 24h before the first MECT treatment, the reduction rate of HDRS-17 at 48h after the last MECT treatment was >=50%, and the total reduction value of ECCA was >=4 points. 5. Age 18-55, male and female; 6. Education level above primary school; 7. The patient or the patient's legal guardian signed the written informed consent for MECT and signed the written informed consent for this study.
Exclusion criteria
Exclusion criteria: 1. Combined with serious physical diseases and diseases that may impair cognitive function (such as stroke, Parkinson's disease, AD/VD, etc.); 2. Subjects could not complete the MATRICS neurocognitive test set (MCCB) at baseline or the total MCCB score at baseline was lower than 40; 3. Subjects were pregnant or nursing, or planned to become pregnant during the study; 4. Participating in other research projects; 5. Receiving CCRT, cognitive correction, TMS and other treatments that may improve cognitive function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ECCA Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| MCCB score;EEG; | — |
Countries
China
Contacts
Public ContactGang Wang
Beijing Anding Hospital
Outcome results
None listed