COVID-19
Conditions
Interventions
Case group:N/A
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age >=18 years, male or female. (2) Patients with COVID-19 meet the diagnostic criteria of the COVID-19 Diagnosis and Treatment Protocol (Trial Version 10). a. Have clinical manifestations associated with COVID-19. b. Have one or more of the following pathogenic and serological findings: positive nucleic acid test; positive antigen test; positive isolation and culture of SARS-CoV-2; four times or more elevated levels of specific IgG antibodies in the recovery phase than in the acute phase. (3) Meet the criteria of moderate severity. a. Moderate: persistent high fever >3 days or (and) cough and shortness of breath, but respiratory rate (RR) 93% when air is inhaled at rest. Characteristic pneumonia manifestations of COVID-19 are seen on imaging. b. Heavy: Adults who meet any of the following criteria and cannot be explained by causes other than COVID-19: (i) shortness of breath with RR >= 30 breaths/min; (ii) oxygen saturation 50% within 24-48 h. c. Critical type: those who meet one of the following conditions: 1. develop respiratory failure and require mechanical ventilation; 2. develop shock; 3. combined with other organ failure requiring ICU monitoring treatment. (4) Sign the telephone informed consent form.
Exclusion criteria
Exclusion criteria: (1) Incomplete medical record information for NRS 2002 or MNA-SF scoring and imaging evaluation. (2) Unwillingness to sign telephone informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm thickness;NRS 2002;MNA-SF;GLIM;Clinical Outcome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutritional Therapy Information;Anthropometric measurements;Laboratory tests;Length of hospitalization; | — |
Countries
China
Contacts
Public ContactChi Yan
Peking University First Hospital
Outcome results
None listed