Fever with thrombocytopenia syndrome
Conditions
Interventions
NA:NA
Sponsors
Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: Subjects must meet all of the following criteria at the same time: 1) Age and gender are not limited; 2) Hospitalized patients diagnosed with fever with thrombocytopenia syndrome have at least one of the following laboratory tests: positive for IgM antibodies specific to bunia virus (SFTSV) with serum fever with thrombocytopenia syndrome or more than 4-fold increase in IgG antibody levels; or SFTSV RNA test positive; or real-time fluorescence quantitative RT-PCR method to detect SFTSV nucleic acid positive; or case specimens isolated into SFTSV.
Exclusion criteria
Exclusion criteria: Exclude patients who meet any of the following criteria: 1) Patients who were positive for other tick-borne pathogens were found by PCR analysis of acute blood samples; 2) It is difficult to carry out outpatient follow-up due to mental disorders, dementia, and diseases that lead to inability to move freely due to combination, such as osteoarthropathy, stroke, pulmonary embolism, etc.; 3) Never followed up on an outpatient basis after discharge, and repeated confirmation by telephone was still unable to get in touch; 4) Because you live in a foreign country, nursing home, or welfare home, you cannot participate in outpatient follow-up after making an appointment by telephone; 5) Currently participating in clinical trials of other drugs or medical devices; 6) The investigators did not consider it suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptoms are of 3 months and 6 months after discharge; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in laboratory indicators at 3 and 6 months after discharge (blood routine, liver and kidney function, electrolytes, myocardial enzyme profile, pancreatic function, coagulation function, lactate, inflammatory factors, blood gas analysis, thromboelastogram);Changes in imaging at 3 and 6 months after discharge: ultrasound (heart, liver), cardiac ultrasound, CT of the lungs, CT/MRI of the abdomen;Treatment plan (time frame: 6 months);Disease outcome (improved discharge, death, automatic discharge) (time frame: 6 months); | — |
Countries
China
Contacts
Public ContactQing ning
Tongji Medical College of Huazhong University of Science & Technology
Outcome results
None listed