Observation of NPA high-flow oxygen supply combined with lumbosacral plexus block for hip and knee arthroplasty in elderly patients with pulmonary diseases

High flow oxygen delivery through nasopharynx airway combined with lumbosacral plexus block for hip and knee replacement in elderly patients with pulmonary diseases

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300068751

Enrollment

Unknown

Registered

2023-02-28

Start date

2023-03-01

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip and knee replacement

Interventions

Group observation:Transnasopharyngeal airway high flow oxygenation combined with lumbosacral plexus block

Eligibility

Sex/Gender

All

Age

65 Years to 89 Years

Inclusion criteria

Inclusion criteria: Patients with unilateral hip surgery, regardless of gender, age 65 to 89 years old, body mass index 18 to 25 kg/?, ASA grade I-III, can complete the Mini Mental State Examination (MMSE) and the Consciousness Disorder Assessment Method (CAM), and MMSE>24 points.

Exclusion criteria

Exclusion criteria: People with fracture, block or puncture site infection, coagulation dysfunction or immune system disease in other parts; Patients with severe heart, liver, kidney and other important organ diseases; Peripheral nervous disease, nervous or mental system disease; Those who are allergic to all drugs, have no chronic pain, drink excessively, or take opioids for a long time; The second operation of hip joint or the amount of bleeding during operation is more than 800ml.

Design outcomes

Primary

Measure	Time frame
PaO2, PaCO2 and oxygenation index in arterial blood of patients at different time points (T1 ~ T7);	—

Secondary

Measure	Time frame
General information and operation: age, gender, BMI, ASA classification, education level, operation time, blood loss, infusion volume, urine volume;MAP, HR, body temperature (ear temperature), arterial blood pH, Lac, BE, HCO3 -, and different degrees of intraoperative hypoxemia (SpO2 < 92%, SpO2 < 88%, SpO2 < 85%) and hypotension (MAP < 80% base value) at the same time point from T1 to T7;Postoperative recovery time, orientation recovery time, retention time in post anesthesia recovery room (PACU), time to get out of bed, anal exhaust time, time to start eating, and time to leave hospital;Intraoperative anesthetic dosage, number and dosage of vasoactive drugs;Adverse reactions such as nausea and vomiting, hypotension, respiratory depression, new pulmonary infection or aggravation of original infection, atelectasis after surgery;	—

Measure

Time frame

General information and operation: age, gender, BMI, ASA classification, education level, operation time, blood loss, infusion volume, urine volume;MAP, HR, body temperature (ear temperature), arterial blood pH, Lac, BE, HCO3 -, and different degrees of intraoperative hypoxemia (SpO2 < 92%, SpO2 < 88%, SpO2 < 85%) and hypotension (MAP < 80% base value) at the same time point from T1 to T7;Postoperative recovery time, orientation recovery time, retention time in post anesthesia recovery room (PACU), time to get out of bed, anal exhaust time, time to start eating, and time to leave hospital;Intraoperative anesthetic dosage, number and dosage of vasoactive drugs;Adverse reactions such as nausea and vomiting, hypotension, respiratory depression, new pulmonary infection or aggravation of original infection, atelectasis after surgery;

—

Countries

China

Contacts

Public ContactDeng Kang

The First Hospital of Jiaxing

jxmzdk@163.com13736446844

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026