Feasibility of modified HFNC combined with lumbosacral plexus block for hip surgery in elderly patients

The feasibility of modified nasal high flow oxygenation combined with lumbosacral plexus block for hip surgery in elderly patients: a randomized controlled study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068748

Enrollment

Unknown

Registered

2023-02-28

Start date

2023-03-01

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip surgery

Interventions

experience group:High flow oxygen delivery through nasopharyngeal airway

control group:Laryngeal mask insertion, keeping spontaneous breathing

Eligibility

Sex/Gender

All

Age

65 Years to 89 Years

Inclusion criteria

Inclusion criteria: Patients with unilateral hip surgery, regardless of gender, age 65 to 89 years old, body mass index 18 to 25 kg/?, ASA grade I-III, can complete the Mini Mental State Examination (MMSE) and the Consciousness Disorder Assessment Method (CAM), and MMSE>24 points.

Exclusion criteria

Exclusion criteria: People with fracture, block or puncture site infection, coagulation dysfunction or immune system disease in other parts; Patients with severe heart, liver, kidney and other important organ diseases; Peripheral nervous disease, nervous or mental system disease; Those who are allergic to all drugs, have no chronic pain, drink excessively, or take opioids for a long time; The second operation of hip joint or the amount of bleeding during operation is more than 800ml.

Design outcomes

Primary

Measure	Time frame
PaO2, PaCO2 and oxygenation index in arterial blood of patients at different time points (T1 ~ T7);	—

Secondary

Measure	Time frame
General information and operation: age, gender, BMI, ASA classification, education level, operation time, blood loss, infusion volume, urine volume;MAP, HR, body temperature (ear temperature), arterial blood pH, Lac, BE, HCO3 -, and different degrees of intraoperative hypoxemia (SpO2 < 92%, SpO2 < 88%, SpO2 < 85%) and hypotension (MAP < 80% base value) at the same time point from T1 to T7.;Postoperative recovery time, orientation recovery time, retention time in the post anesthesia recovery room (PACU), time to start getting out of bed, time to exhaust anus, time to start eating, and time to leave hospital.;Intraoperative anesthetic dosage, number and dosage of vasoactive drugs.;Adverse reactions such as nausea and vomiting, hypotension, respiratory depression, pulmonary infection, atelectasis, etc.;	—

Measure

Time frame

General information and operation: age, gender, BMI, ASA classification, education level, operation time, blood loss, infusion volume, urine volume;MAP, HR, body temperature (ear temperature), arterial blood pH, Lac, BE, HCO3 -, and different degrees of intraoperative hypoxemia (SpO2 < 92%, SpO2 < 88%, SpO2 < 85%) and hypotension (MAP < 80% base value) at the same time point from T1 to T7.;Postoperative recovery time, orientation recovery time, retention time in the post anesthesia recovery room (PACU), time to start getting out of bed, time to exhaust anus, time to start eating, and time to leave hospital.;Intraoperative anesthetic dosage, number and dosage of vasoactive drugs.;Adverse reactions such as nausea and vomiting, hypotension, respiratory depression, pulmonary infection, atelectasis, etc.;

—

Countries

China

Contacts

Public ContactDeng Kang

The First Hospital of Jiaxing

jxmzdk@163.com13736446844

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026