varicocele
Conditions
Interventions
Observation group:none
Sponsors
Xiangya Hospital Central South University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Varicocele diagnosed by ultrasound. Surgical indications for varicocele in accordance with CUA2019 guidelines. Karnofsky score (Annex 1) = 70. From April 2020 to April 2022, he was admitted to Xiangya Hospital of Central South University. Underwent microvaricocele shunt in Xiangya Hospital of Central South University. Laboratory indicators: neutrophil count (ANC) = 1000/mm3, platelet count = 100000/mm3, hemoglobin = 9.0g/dl, bilirubin = 1.5 times of normal limit (normal range specified by the organization), glutamic oxaloacetic transaminase (AST), glutamic pyruvic transaminase (ALT) and alkaline phosphatase = 2.5 times of normal limit, creatinine (Scr) = 1.5mg/dL. CCR = 60ml / min (GC or GC+ICI) or CCR = 30ml / min (ICI) (using Cockcroft-Gault formula: creatinine clearance rate for men = (140-age) * body weight (kg) / 72 * serum creatinine (mg/dl) or creatinine clearance rate = (140-age) * body weight (kq) / [0.818 * serum creatinine (umol/L)])
Exclusion criteria
Exclusion criteria: Lack of clinical and follow-up data. Severe heart disease (i.e. class III and above cardiac function). Severe medical or mental illness, including severe active infections. He has received other surgical treatment within 4 weeks. The following symptoms occur within 6 months: myocardial infarction, severe / unstable angina pectoris, coronary artery / peripheral artery bypass, symptomatic congestive heart failure, cerebrovascular accident or transient ischemic attack. Persistent arrhythmia = 2 grade (NCI CTCAE Version 4.0grade). Diseases or infections related to human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS). He participated in other clinical trials at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain relief;Improvement of semen parameters;Operative complication; | — |
Secondary
| Measure | Time frame |
|---|---|
| Relapse rate;satisfaction with the cosmetic outcome;Operation time;hospitalization time after surgery;time to return to normal activities;postoperative pain; | — |
Countries
China
Contacts
Public ContactXiongbing Zu
Xiangya Hospital Central South University
Outcome results
None listed