Skip to content

Clinical evaluation and mechanism of fNIRS-based guided bilateral iTBS in stroke patients with dysphagia

Clinical evaluation and mechanism of fNIRS-based guided bilateral iTBS in stroke patients with dysphagia

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068730
Enrollment
Unknown
Registered
2023-02-28
Start date
2023-02-28
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Bilateral iTBS group.:Bilateral iTBS
Bilateral rTMS group :Bilateral rTMS
Sham group :False Stimulus

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Unilateral stroke (hemorrhagic (without cranial decompression surgery), ischemic) meeting the diagnostic criteria for stroke; (CT or MRI confirmation is required to keep files for further subgroup analysis) (2) First onset, 2 weeks = duration of stroke = 6 months. (3) Age 18 years or older. (4) infiltration and/or aspiration confirmed by electronic fiberoptic endoscopic evaluation of swallowing (FEES) (5) Puddlefield drinking water test = grade 3. (6) Family members or the patient himself signed the relevant informed consent.

Exclusion criteria

Exclusion criteria: (1) Swallowing problems caused by other neurological disorders, such as Parkinson's disease, Alzheimer's disease, motor neuron disease, cranial trauma, and patients with cerebellar or brainstem strokes. (2) History of intractable epilepsy. (3) Intracranial metal implants and/or cardiac metal implants. (4) Pregnancy. (5) Patients with unstable vital signs or in the acute phase of the disease. (6) Patients with poor cognitive function, unable to cooperate with relevant examinations and treatments.

Design outcomes

Primary

MeasureTime frame
standardized swallowing assessment;penetration-Aspiration Scale;the Murray Secretion Scale;

Secondary

MeasureTime frame
motor evoked potentials;Functional near infrared spectroscopy;Functional Magnetic Resonance;

Countries

China

Contacts

Public ContactWang Yinxu

Affiliated hospital of north sichuan medical college

34089681@qq.com13438781951

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026