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Effect of Esketamine on gastrointestinal function in patients undergoing robot-assisted laparoscopic radical prostatectomy

Effect of Esketamine on gastrointestinal function in patients undergoing robot-assisted laparoscopic radical prostatectomy

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068716
Enrollment
Unknown
Registered
2023-02-28
Start date
2023-02-28
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prostatic cancer

Interventions

Esketamine group(group C):Before anesthesia induction: group C was injected with 0.2mg/kg of Esketamine (diluted to 1mg/ml with normal saline) intravenously, which was completed within 5min, and then
Control group (group D):An equal volume of saline was injected i.v

Sponsors

Nanjing Drum Tower Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 90 Years

Inclusion criteria

Inclusion criteria: ? The histopathological examination of prostate biopsy before operation showed that it was prostate cancer; ? Robot-assisted laparoscopic radical resection of prostate cancer was performed on a scheduled basis; ? Willing to participate in the study and sign the informed consent form

Exclusion criteria

Exclusion criteria: ? Serious dysfunction of heart, lung and other important organs; ? History of previous abdominal surgery or chronic digestive system disease; ? Preoperative anemia and hypoproteinemia

Design outcomes

Primary

MeasureTime frame
Recovery time of bowel exhaust and defecation after operation;

Secondary

MeasureTime frame
Plasma endotoxin;

Countries

China

Contacts

Public ContactCUI Shihe

Nanjing Drum Tower Hospital

cuishihe@126.com13451906001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026